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Am J Hypertens. 1995 Oct;8(10 Pt 1):1046-50. Low dose hydrochlorothiazide (12.5 to 25 mg daily) as monotherapy in black patients with mild to moderate hypertension. Assessment by ambulatory blood pressure monitoring. Skoularigis J(1), Strugo V, Chopamba A, Setekge S, Sareli P. Author information: (1)Division of
Associate Professor in the Division of General Internal Medicine at the University of Alberta and contributes to the CHEP obesity guidelines. Copyright and License Chlorthalidone reduces systolic blood pressure (BP) better than HCTZ at equivalent doses with similar effects on potassium levels: -25 mg of chlorthalidone,
Jan 26, 2011 In their meta-analysis, Messerli et al scrutinized the antihypertensive efficacy of HCTZ as assessed by 24-hour ABPM. In 14 studies, with an HCTZ dose of 12.5 to 25 mg in 1234 patients, the decrease in 24-hour ABPM was "a meager 6.5/4.5 mm Hg," they observe.
May 15, 2000 Diuretics are effective antihypertensive drugs. Treatment with a diuretic such as hydrochlorothiazide results in a dose-dependent blood pressure reduction that levels off with higher dosages (Table 2).11 In long-term trials, diuretics have been shown to reduce the incidence of stroke, congestive heart failure,
Therefore it seems rational to recommend that diuretic treatment with chlorthalidone should start with 6.25 mg in the elderly and 12.5 mg in younger patients, with a maximum dose of 25 mg/d, whereas the starting doses of hydrochlorothiazide should be 12.5 mg in the elderly and 25 mg in younger patients, with a maximum
Mar 8, 2017 Thiazide and thiazide-like diuretics have been a mainstay of the therapy of primary hypertension. The most popular agent in this class, hydrochlorothiazide, was traditionally used in doses of 50 to 100 mg/day. These doses were associated with metabolic and electrolyte complications. Low-dose therapy has
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Hydrochlorothiazide is used to treat high blood pressure (hypertension). Hydrochlorothiazide is also used to treat fluid retention (edema) in people with congestive heart failure,

Dosing chart for thiazide diuretics including dosage forms, dosing recommendations, food effects, generic availability, and more. Hypertension. Dosing: HCTZ 12.5 - 50 mg once daily; Fosinopril 10 - 80 mg once daily; In trials, the maximum dose used was 40/37.5 mg once daily. YES/$, FOOD. May take without regard to
Jun 1, 1986 Abstract. In a double-blind crossover study, 13 patients with pretreatment diastolic blood pressure between 95 and 109 mm Hg received nadolol, 80 mg/day, plus placebo of hydrochlorothiazide and nadolol, plus three different doses of active hydrochlorothiazide. Patients remained on each active regimen